六种动脉粥样硬化标志物的研究进展

被引:9
作者
季茳
张春妮
机构
[1] 南京军区南京总医院解放军临床检验医学研究所检验科
关键词
动脉粥样硬化; 心血管疾病; 标志物; 同型半胱氨酸; C反应蛋白; 3纤维蛋白原; 载脂蛋白B; 载脂蛋白A-I; 脂蛋白相关磷脂酶A2; 微小核糖核酸;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
摘要
<正>心血管疾病(cardiovascular disease,CVD)占全球致死疾病的50%,是西方国家的主要死亡原因[1]。近年来,由于国人饮食与生活习惯的改变,动脉粥样硬化(atherosclerosis,AS)在我国的发病率和死亡率均逐年上升且呈"年轻化"趋势。1999年,Ross[2]提出了"AS是一种炎症性疾病"的学说,认为AS是源于内皮功能障碍的慢性、进行性、炎症性疾病,其形成因素包括细胞聚集和增殖、斑块形成、血管重塑、炎症
引用
收藏
页码:59 / 62
页数:4
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  • [1] 载脂蛋白E基因敲除小鼠血脂及心肌酶学的测定及意义
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    [J]. 现代生物医学进展, 2010, 10 (04) : 639 - 641
  • [2] 细胞流式术检测同型半胱氨酸诱导血管平滑肌细胞凋亡的研究
    张静
    徐会圃
    吴琪
    [J]. 滨州医学院学报, 2009, 32 (06) : 417 - 419
  • [3] 血清载脂蛋白A-1、载脂蛋白B和脂蛋白(a)与冠心病相关性的临床分析
    王晓晨
    徐岩
    程自平
    许邦龙
    陈斌
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    伍梦佐
    林先和
    朱润硕
    [J]. 安徽医科大学学报, 2009, 44 (03) : 395 - 398
  • [4] Plasma Lp-PLA2 in Acute Coronary Syndrome: Association with Major Adverse Cardiac Events in a Community-Based Cohort[J] . Li,Yu,Gu.Postgraduate Medicine . 2010 (4)
  • [5] C-reactive protein: Risk factor, biomarker and/or therapeutic target?[J] . Jacques Genest.Canadian Journal of Cardiology . 2010
  • [6] Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review[J] . Marianne Benn.Atherosclerosis . 2009 (1)
  • [7] Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study[J] . Matthew J McQueen,Steven Hawken,Xingyu Wang,Stephanie Ounpuu,Allan Sniderman,Jeffrey Probstfield,Krisela Steyn,John E Sanderson,Mohammad Hasani,Emilia Volkova,Khawar Kazmi,Salim Yusuf.The Lancet . 2008 (9634)
  • [8] Review of the Evidence for the Clinical Utility of Lipoprotein-Associated Phospholipase A 2 as a Cardiovascular Risk Marker[J] . Marshall A. Corson,Peter H. Jones,Michael H. Davidson.The American Journal of Cardiology . 2008 (12)
  • [9] Common Genetic Polymorphisms and Haplotypes of Fibrinogen Alpha, Beta, and Gamma Chains Affect Fibrinogen Levels and the Response to Proinflammatory Stimulation in Myocardial Infarction Survivors[J] . Bénédicte Jacquemin,Charalambos Antoniades,Fredrik Nyberg,Estel Plana,Martina Müller,Sonja Greven,Veikko Salomaa,Jordi Sunyer,Tom Bellander,Alexandros-Georgios Chalamandaris,Ricardo Pistelli,Wolfgang Koenig,Annette Peters.Journal of the American College of Cardiology . 2008 (11)
  • [10] Estimating LDL ApoB: Infomania or Clinical Advance?[J] . Burnett,John R,Watts,Gerald F.Clinical Chemistry . 2008 (5)