9F系列海洋真菌代谢产物分离纯化及稻瘟霉活性研究

被引:8
作者
赵玲玲
张惠平
机构
[1] 复旦大学药学院天然药物化学教研室
关键词
海洋真菌; 代谢产物; 稻瘟霉;
D O I
10.16333/j.1001-6880.2005.06.001
中图分类号
R284 [中药化学];
学科分类号
摘要
自帕劳群岛的3株9F系列海洋真菌中分离得到4个化合物,采用MS,NMR等光谱技术,确定结构分别为trans-dehydrocurvularin(1),terrein(2),paxilline(3)和citreopyrone(4),其对稻瘟霉P2b菌株的最小抑制浓度分别为:10,100,1.56,3.12μg/mL。其中化合物1是首次从海洋真菌中分离得到。
引用
收藏
页码:677 / 680
页数:4
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