鼻咽癌的治疗进展

被引：9

作者：

孙健达

李德锐

机构：

[1] 汕头大学医学院附属肿瘤医院放疗科

来源：

医学综述 | 2010年 / 16卷 / 21期

关键词：

鼻咽肿瘤/放射疗法; 调强适形放射治疗; 化学治疗; 生物治疗;

D O I：

暂无

中图分类号：

R739.63 [咽肿瘤];

学科分类号：

摘要：

近10年来鼻咽癌的治疗取得了较大进展。随着调强适形放射治疗逐步广泛地应用,鼻咽癌的局部控制率得到显著提高。与此同时,调强适形放射治疗减少了周围正常组织器官的放射损伤,大大提高了患者的生存质量。放化疗综合治疗不但可以降低肿瘤的局部区域复发率及远处转移率,而且还在一定程度上提高了总生存率,因此对于晚期鼻咽癌患者采用放化疗综合治疗已成为标准的治疗模式。同时生物治疗也取得一定进展,相信在鼻咽癌治疗中将会发挥越来越重要的作用。

引用

页码：3255 / 3259

页数：5

共 10 条

[1]

305例鼻咽癌调强放疗预后因素分析[J]. 韩露,林少俊,潘建基,陈传本,张瑜,张秀春,廖希一,陈奇松.癌症. 2010(02)

[2]

初治鼻咽癌调强放疗与常规放疗的同期对照研究[J]. 张瑜,林志安,潘建基,郑茁,杨凌,林少俊,郑飞.癌症. 2009(11)

[3]

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival[J] . James A Bonner,Paul M Harari,Jordi Giralt,Roger B Cohen,Christopher U Jones,Ranjan K Sur,David Raben,Jose Baselga,Sharon A Spencer,Junming Zhu,Hagop Youssoufian,Eric K Rowinsky,K Kian Ang.Lancet Oncology . 2010 (1)

[4]

Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: Initial report on a randomized controlled clinical trial[J] . Edmond H.N. Pow,Dora L.W. Kwong,Anne S. McMillan,May C.M. Wong,Jonathan S.T. Sham,Lucullus H.T. Leung,W. Keung Leung.International Journal of Radiation Oncology, Biology, Physics . 2006 (4)

[5] Preliminary results of a randomized study (NPC-9902 trial) on therapeutic gain by concurrent chemotherapy and/or accelerated fractionation for locally advanced nasopharyngeal carcinoma [J].

Lee, Anne W. M. ;

Tung, Stewart Y. ;

Chan, Anthony T. C. ;

Chappell, Rick ;

Fu, Yiu-Tong ;

Lu, Tai-Xiang ;

Tan, Terence ;

Chua, Daniel T. T. ;

O'Sullivan, Brian ;

Xu, Shirley L. ;

Pang, Ellie S. Y. ;

Sze, Wai-Man ;

Leung, To-Waj ;

Kwan, Wing-Hong ;

Chan, Paddy T. M. ;

Liu, Xiu-Fang ;

Tan, Eng-Huat ;

Sham, Jonathan S. T. ;

Siu, Lillian ;

Lau, Wai-Hon .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 66 (01) :142-151

[6]

Improvement of survival after addition of induction chemotherapy to radiotherapy in patients with early-stage nasopharyngeal carcinoma: Subgroup analysis of two Phase III trials[J] . Daniel T.T. Chua,Jun Ma,Jonathan S.T. Sham,Hai-Qiang Mai,Damon T.K. Choy,Ming-Huang Hong,Tai-Xiang Lu,Gordon K.H. Au,Hua-Qing Min.International Journal of Radiation Oncology, Biology, Physics . 2006 (5)

[7]

Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients[J] . Bertrand Baujat,Hélène Audry,Jean Bourhis,Anthony T.C. Chan,Haluk Onat,Daniel T.T. Chua,Dora L.W. Kwong,Muhyi al-Sarraf,Kwan-Hwa Chi,Masato Hareyama,Sing F. Leung,Kullathorn Thephamongkhol,Jean-Pierre Pignon.International Journal of Radiation Oncology, Biology, Physics . 2006 (1)

[8] Treatment outcomes and late complications of 849 patients with nasopharyngeal carcinoma treated with radiotherapy alone [J].

Yeh, SA ;

Tang, Y ;

Lui, CC ;

Huang, YJ ;

Huang, EY .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 62 (03) :672-679

[9]

Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience[J] . Nancy Lee,Ping Xia,Jeanne M Quivey,Khalil Sultanem,Ian Poon,Clayton Akazawa,Pam Akazawa,Vivian Weinberg,Karen K Fu.International Journal of Radiation Oncology, Biology, Physics . 2002 (1)

[10]

Effect of recombinant adenovirus-p53 combined with radiotherapy on long-term prognosis of advanced nasopharyngeal carcinoma. Pan JJ,Zhang SW,Chen CB, et al. Journal of Clinical Oncology . 2009

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