介入治疗后冠状动脉再狭窄与冠心病易患因素吸烟关系分析

被引:13
作者
蔡煦
沈卫峰
张大东
张建盛
于金德
龚兰生
机构
[1] 上海第二医科大学附属瑞金医院心脏科
关键词
再狭窄; PTCA; 易患因素;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
摘要
目的 探讨国人冠心病介入治疗后再狭窄与冠心病易患因素吸烟关系。方法 冠心病介入治疗35 2例中 ,选择连续 6 5例 (86个冠脉狭窄病变 )术后 3~ 16个月随访重复冠脉造影者 ,冠脉定量分析 (QCA)术前、术后和随访复查冠脉造影图象 ,并分析再狭窄发生率及随访时内径丢失与冠心病易患因素的关系。结果 再狭窄发生时间与吸烟史、多个易患因素、多支病变、病变类型、前降支病变、随访期尿酸呈正性相关 ,与支架置入呈负性相关。吸烟者 (37个病变 ) 16个月再狭窄累计发生率 (88.33 % )高于非吸烟者 (4 9个病变 ,6 6 .49% ,P<0 .0 5 ,Kaplan Meier法和log rank检验 ) ,再狭窄者吸烟量大 ;吸烟史者随访最小内径较小 ,但晚期内径丢失大于非吸烟者。结论 冠心病易患因素与介入后再狭窄发生可能有密切关系 ,多个易患因素特别是吸烟史 ,再狭窄可能性大
引用
收藏
页码:461 / 464
页数:4
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