细胞因子调控睾丸支持细胞紧密连接的研究进展

被引：14

作者：

秦茂

张秀平

刘保兴

机构：

[1] 中日友好医院男科

来源：

中国男科学杂志 | 2014年 / 28卷 / 10期

关键词：

肿瘤坏死因子α; 转化生长因子β; 白细胞介素类; 塞尔托利细胞; 血睾屏障;

D O I：

暂无

中图分类号：

R321.1 [生殖细胞];

学科分类号：

100107 [人体解剖与组织胚胎学（人体解剖学、组织与胚胎学）];

摘要：

<正>睾丸支持细胞即Sertoli细胞的立体构型比较复杂,在形态上呈不规则锥体形,基部紧贴基膜,顶部伸达管腔,侧面和腔面有许多不规则凹陷,内镶嵌着生精细胞并为其提供结构上的支持与定位。睾丸支持细胞之间通过紧密连接形成的血睾屏障(blood-testis barrier,BTB)将生精上皮分为基底室和近腔室,处于细线期和细线前期的精母细胞必须从生精上皮的基底小室进入近腔小室,这样形态上发育完全的精子才能在精子释放时进入到生精小管的内腔,BTB适时的开闭对精子的发生有至关重要的作用。精子的发生

引用

页码：65 / 67

页数：3

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