质谱技术在现代营养学和食品分析检测中的应用

被引:3
作者
周蕴华
尹慧勇
机构
[1] 中国科学院上海生命科学研究院营养科学研究所中国科学院营养与代谢重点实验室营养与代谢质谱研究中心脂肪酸代谢与营养相关疾病研究组
关键词
质谱技术; 营养素; 脂质组学; 食物组学; 食品安全;
D O I
10.13376/j.cbls/2013.02.009
中图分类号
R151 [营养学];
学科分类号
100403 ;
摘要
随着质谱仪器和技术的高速发展,现代营养学研究和食品分析检测领域不断拓展,不仅深入到营养相关疾病分子机制的研究,而且建立了以分析复杂基质中复杂食物成分为主的食物组学(Foodomics)。本文概述了近年来现代质谱分析技术在蛋白质、糖类、维生素和微量元素等食物营养素检测方面的进展,着重介绍了基于质谱的脂质组学运用于营养相关疾病机制研究中所获得的新发现。针对目前公众关注的食品安全问题,本文也阐述了质谱强大的分析能力在监测食品中有害物质残留,检测食品中天然过敏原的存在和判断食品污染中的微生物致病原来源的作用。总之,质谱技术以其高灵敏度、高精度和准确度以及高通量越来越成为营养科学和食品科学不可或缺的分析手段。
引用
收藏
页码:240 / 247
页数:8
相关论文
共 25 条
[1]   电感耦合等离子体-质谱法在尿液微量元素测试中的应用 [J].
何晓文 ;
许光泉 ;
黎艳红 ;
满铭铎 .
光谱实验室, 2010, 27 (01) :316-320
[2]   Determination of multi-class pesticides in wines by solid-phase extraction and liquid chromatography-tandem mass spectrometry [J].
Economou, Anastasios ;
Botitsi, Helen ;
Antoniou, Spyros ;
Tsipi, Despina .
JOURNAL OF CHROMATOGRAPHY A, 2009, 1216 (31) :5856-5867
[3]  
Dispersive solid-phase extraction followed by liquid chromatography–tandem mass spectrometry for the multi-residue analysis of pesticides in raw bovine milk[J] . Thierry Dagnac,Maria Garcia-Chao,Paula Pulleiro,Carmen Garcia-Jares,Maria Llompart.Journal of Chromatography A . 2009 (18)
[4]  
Quantification of F 2 -isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography–mass spectrometry (GC-MS) method[J] . Wei Liu,Jason D. Morrow,Huiyong Yin.Free Radical Biology and Medicine . 2009 (8)
[5]  
Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism[J] . Cell . 2008 (6)
[6]  
Multi-class determination of antimicrobials in meat by pressurized liquid extraction and liquid chromatography–tandem mass spectrometry[J] . Vanesa Carretero,Cristina Blasco,Yolanda Picó.Journal of Chromatography A . 2008 (1)
[7]  
Selective and rapid immunomagnetic bead-based sample treatment for the liquid chromatography–electrospray ion-trap mass spectrometry detection of Ara h3/4 peanut protein in foods[J] . Maria Careri,Lisa Elviri,Jesse Boquett Lagos,Alessandro Mangia,Francesca Speroni,Mattia Terenghi.Journal of Chromatography A . 2008 (2)
[8]  
Use of specific peptide biomarkers for quantitative confirmation of hidden allergenic peanut proteins Ara h 2 and Ara h 3/4 for food control by liquid chromatography–tandem mass spectrometry[J] . M. Careri,A. Costa,L. Elviri,J.-B. Lagos,A. Mangia,M. Terenghi,A. Cereti,L. Perono Garoffo.Analytical and Bioanalytical Chemistry . 2007 (6)
[9]  
Method to determine 4‐oxo‐retinoic acids, retinoic acids and retinol in serum and cell extracts by liquid chromatography/diode‐array detection atmospheric pressure chemical ionisation tandem mass spectrometry[J] . RalphRühl.Rapid Commun. Mass Spectrom. . 2006 (16)
[10]  
Analysis of native milk oligosaccharides directly from thin-layer chromatography plates by matrix-assisted laser desorption/ionization orthogonal-time-of-flight mass spectrometry with a glycerol matrix[J] . Klaus Dreisewerd,Stefanie K?lbl,Jasna Peter-Katalini?,Stefan Berkenkamp,Gottfried Pohlentz.Journal of the American Society for Mass Spectrom . 2006 (2)