急性肾损伤发病机制的研究进展

被引:8
作者
尹永杰
张京晓
机构
[1] 吉林大学第二医院急救医学科
关键词
D O I
暂无
中图分类号
R692 [肾疾病];
学科分类号
摘要
<正>急性肾损伤(acute kidney injury,AKI)是急性肾功能衰竭(acute renal failure,ARF)的早期阶段,此时肾小球滤过率和尿量通常尚未发生明显的改变。AKI在住院患者中总体发生率为1%~7%,在ICU病房中AKI的发生率为25%,约有5%的患者需要肾脏替代治疗。在美国肾脏替代治疗是唯一被联邦食品药品管理局(FDA)认可的治疗AKI的有效措施。即使肾脏替代治疗得到了广泛的应用,在ICU病房AKI的病死率仍高达80%,AKI发病率
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页码:324 / 327
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