长链非编码RNA在前列腺癌中的研究进展

被引:1
作者
巴音 [1 ]
云志中 [2 ]
黄翔华 [2 ]
马可为 [2 ]
机构
[1] 内蒙古医科大学研究生学院
[2] 内蒙古自治区泌尿外科研究所
关键词
前列腺癌; 长链非编码RNA; 生物标志物; 治疗靶点;
D O I
10.16096/J.cnki.nmgyxzz.2021.53.01.008
中图分类号
R737.25 [前列腺肿瘤];
学科分类号
100214 [肿瘤学];
摘要
研究表明,人类基因组中某些特定的非蛋白质编码区(Non-coding region)与肿瘤的发生、发展密切相关,其中最丰富的一类就是长链非编码RNA(lncRNA),它们与前列腺癌(PCa)的关系得到了越来越多的关注。本文对lncRNA PCa3、PCGEM1、SChLAP1、GAS5、PCAT1、MEG3在前列腺癌发生、发展中的功能和作用机制进行综述,并对lncRNA在前列腺癌早期诊断、预后及靶向治疗中的应用进行了展望。
引用
收藏
页码:24 / 27
页数:4
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