乳腺癌干性表型癌细胞的临床意义

被引：6

作者：

张众 ^{[1
]}

谢丰培 ^{[1
]}

Gary GuishanXiao ^{[2
]}

机构：

[1] 大连医科大学病理学教研室

[2] Creighton University Medical Center

来源：

临床与实验病理学杂志 | 2014年 / 30卷 / 01期

关键词：

乳腺肿瘤; 干性表型; 靶基因;

D O I：

暂无

中图分类号：

R737.9 [乳腺肿瘤];

学科分类号：

100214 [肿瘤学];

摘要：

<正>乳腺癌是女性最常见的恶性肿瘤,病死率居全球首位。近20年,由于早期发现和辅助治疗的改进,乳腺癌的治疗疗效已明显提升,但很多患者仍面临复发的恐惧和死亡的威胁[1]。现阶段,乳腺癌总体复发率约40%,其中60%70%的患者发生远处转移[2]。应用常规化疗药物联合治疗,HER-2阳性早期转移性乳腺癌对trastuzumab的反应率为50%84%,但疗程开始1年内药物即对患者失效。目前,

引用

页码：1 / 5

页数：5

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