磁共振成像评价急性胰腺炎的严重程度与肝功能的相关性研究

被引：19

作者：

唐伟

张小明

黄小华

肖波

曾南林

翟昭华

机构：

[1] 川北医学院附属医院放射科

来源：

磁共振成像 | 2010年 / 1卷 / 01期

关键词：

胰腺炎,急性坏死性; 磁共振成像; 疾病严重程度指数; 肝功能衰竭;

D O I：

暂无

中图分类号：

R576 [胰腺疾病]; R445.2 [核磁共振成像];

学科分类号：

100201 [内科学]; 100231 [临床病理学];

摘要：

目的探讨急性胰腺炎(AP)严重程度的MRI评价与肝功能指标的相关性。方法64例急性胰腺炎患者,根据MRI表现,分为水肿型和坏死型。按照MR严重程度指数(MRSI)评分,分为轻度(0～3分)、中度(4～6分)、重度(7～10分)。分析其肝功能指标(ALT和AST),并与MRSI比较。结果在64例AP中,56例为水肿型,8例为坏死型。坏死型APALT、AST升高的发生率均为100%,明显大于水肿型的55.4%(ALT)和60.7%(AST)(分别为P=0.014,P=0.027)。在MRSI上,轻、中、重度APALT和AST升高的发生率分别为48.8%和53.5%、73.7%和78.9%,以及100%和100%。随MRSI评分的增加,肝功异常有增多的趋势,但差异无统计学意义。结论MRI能够在一定程度上预测坏死型AP所伴发的肝脏功能受损,但MRSI尚不能作为预测AP肝脏功能受损的指标。

引用

收藏

页码：46 / 49

页数：4

相关论文

共 10 条

[1]

肝病酶学指标及临床应用进展 [J].

孙志强 ;

毛远丽 .

中华检验医学杂志, 2005, (06) :659-663

[2]

Prospective evaluation of nonenhanced MR imaging in acute pancreatitis [J].

Viremouneix, Loic ;

Monneuse, Olivier ;

Gautier, Guillaume ;

Gruner, Laurent ;

Giorgi, Roch ;

Allaouchiche, Bernard ;

Pilleul, Frank .

JOURNAL OF MAGNETIC RESONANCE IMAGING, 2007, 26 (02) :331-338

[3]

Staging of severity and prognosis of acute pancreatitis by computed tomography and magnetic resonance imaging- A comparative study [J].

Arvanitakis, M. ;

Koustiani, G. ;

Gantzarou, A. ;

Grollios, G. ;

Tsitouridis, I. ;

Haritandi-Kouridou, A. ;

Dimitriadis, A. ;

Arvanitakis, C. .

DIGESTIVE AND LIVER DISEASE, 2007, 39 (05) :473-482

[4]

Computed tomography severity index is an early prognostic tool for acute pancreatitis [J].

Vriens, PW ;

van de Linde, PV ;

Slotema, ET ;

Warmerdam, PE ;

Breslau, PJ .

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2005, 201 (04) :497-502

[5]

A comparison of the Ranson, Glasgow, and APACHE II scoring systems to a multiple organ system scorein predicting patient outcome in pancreatitis [J].

Taylor, SL ;

Morgan, DL ;

Denson, KD ;

Lane, MM ;

Pennington, LR .

AMERICAN JOURNAL OF SURGERY, 2005, 189 (02) :219-222

[6]

Computed tomography and magnetic resonance imaging in the assessment of acute pancreatitis [J].

Arvanitakis, M ;

Delhaye, M ;

De Maertelaere, V ;

Bali, M ;

Winant, C ;

Coppens, E ;

Jeanmart, J ;

Zalcman, M ;

Van Gansbeke, D ;

Devière, J ;

Matos, C .

GASTROENTEROLOGY, 2004, 126 (03) :715-723

[7]

How often are liver function tests normal in acute biliary pancreatitis? [J].

Dholakia, K ;

Pitchumoni, CS ;

Agarwal, N .

JOURNAL OF CLINICAL GASTROENTEROLOGY, 2004, 38 (01) :81-83

[8]

Prediction of bile duct stones and complications in gallstone pancreatitis using early laboratory trends [J].

Cohen, ME ;

Slezak, L ;

Wells, CK ;

Andersen, DK ;

Topazian, M .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2001, 96 (12) :3305-3311

[9]

Elastase mimics pancreatitis-induced hepatic injury via inflammatory mediators [J].

Jaffray, C ;

Yang, J ;

Norman, J .

JOURNAL OF SURGICAL RESEARCH, 2000, 90 (02) :95-101

[10]

The effect of gabexate mesilate on pancreatic and hepatic microcirculation in acute experimental pancreatitis in rats [J].

Chen, HM ;

Hwang, TL ;

Chen, MF .

JOURNAL OF SURGICAL RESEARCH, 1996, 66 (02) :147-153