白藜芦醇的雌激素样作用研究

被引:40
作者
刘兆平
于波
李文仙
孙静
黄建
霍军生
刘长兴
不详
机构
[1] 中国预防医学科学院营养与食品卫生研究所
[2] 龙兴生物工程研究所 北
关键词
白藜芦醇; 雌激素样作用; 小鼠;
D O I
暂无
中图分类号
Q946 [植物生物化学];
学科分类号
摘要
为研究白藜芦醇在体内的雌激素样作用 ,给刚断乳小鼠分别皮下注射和灌胃不同剂量的白藜芦醇 ,观察该物质对子宫和阴道的影响。结果显示 ,2 0mg kg .BW的白藜芦醇可明显促进未成熟小鼠阴道开口 (P <0 0 5 )和阴道上皮角化 ,显著增加子宫重量及其系数 (P <0 0 5 ,P <0 0 1) ,并可使子宫内膜柱状上皮增厚或腺体增生。结果表明白藜芦醇在体内具有雌激素样作用。而口服白藜芦醇的雌激素活性明显弱于皮下注射
引用
收藏
页码:188 / 190
页数:3
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