海马与帕金森病

被引：5

作者：

王钰

张本恕

机构：

[1] 天津医科大学总医院神经内科

来源：

国际神经病学神经外科学杂志 | 2014年 / 41卷 / 01期

关键词：

海马; 帕金森病; 多巴胺; 非运动症状; 认知障碍;

D O I：

10.16636/j.cnki.jinn.2014.01.020

中图分类号：

R742.5 [震颤麻痹综合征];

学科分类号：

1002 ;

摘要：

帕金森病的主要病理特点为多巴胺能神经元的缺失。近年研究发现,海马可通过多巴胺及其它递质传递系统间复杂的传导环路,在突触可塑性、适应性记忆以及动机行为中发挥重要作用。对于帕金森病患者,海马与冲动控制障碍、嗅觉减退、疲劳等非运动症状有关。进一步探讨海马与帕金森病的关系以及相关机制,将有利于对帕金森病非运动症状更深入的认识,并可为其治疗提供新的思路。

引用

页码：81 / 84

页数：4

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