抗NMDA受体脑炎诊治进展

被引：13

作者：

官文征 ^{[1
]}

王华 ^{[2
]}

机构：

[1] 中国医科大学

[2] 中国医科大学附属盛京医院小儿神经内科

来源：

中国实用儿科杂志 | 2012年 / 12期

关键词：

抗NMDA受体; 脑炎; 边缘叶脑炎; 运动障碍;

D O I：

暂无

中图分类号：

R725.1 [小儿传染病];

学科分类号：

100201 [内科学];

摘要：

<正>2005年Vitaliani等[1]发现一组均伴良性畸胎瘤的年轻女性患者体内存在一种不明抗原,主要在海马神经元细胞膜表达,可能是一种新的边缘叶副肿瘤性脑炎。这种脑炎病情危重,有潜在致死风险,且需接受长期重症监护治疗,但在接受肿瘤切除和免疫治疗后多数患者最终康复。2007年Dalmau等[2]在此类患者体内发现了抗海马和前额

引用

页码：950 / 953

页数：4

共 13 条

[1]

抗NMDA受体脑炎新进展 [J].

刘娟丽 ;

王莉 ;

杨春晓 .

中风与神经疾病杂志, 2012, 29 (02) :190-192

[2]

Extreme delta brush: A unique EEG pattern in adults with anti-NMDA receptor encephalitis[J] Sarah E. Schmitt;Kimberly Pargeon;Eric S. Frechette;Lawrence J. Hirsch;Josep Dalmau;Daniel Friedman Neurology 2012,

[3]

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis[J] Josep Dalmau;Eric Lancaster;Eugenia Martinez-Hernandez;Myrna R Rosenfeld;Rita Balice-Gordon Lancet Neurology 2011,

[4]

Prolonged Follow-up and CSF Antibody Titers in a Patient With Anti-NMDA Receptor Encephalitis[J] Eric S. Frechette;Lei Zhou;Steven L. Galetta;Lei Chen;Josep Dalmau Neurology 2011,

[5]

N-methyl D-aspartate receptor encephalitis: A new addition to the spectrum of autoimmune encephalitis[J] Boby Maramattom;Anu Jacob Annals of Indian Academy of Neurology 2011,

[6]

RESPONSE TO IMMUNOTHERAPY IN A 20-MONTH-OLD BOY WITH ANTI-NMDA RECEPTOR ENCEPHALITIS[J] Joel A. Vilensky;Roger C. Duvoisin Neurology 2011,

[7]

Anti-NMDA Receptor Encephalitis With Atypical Brain Changes on MRI[J] Sophelia H.S. Chan;Virginia C.N. Wong;Cheuk-wing Fung;Russell C. Dale;Angela Vincent Pediatric Neurology 2010,

[8]

Cortical Hypometabolism Demonstrated by PET in Relapsing NMDA Receptor Encephalitis[J] Sekhar C. Pillai;Deepak Gill;Richard Webster;Robert Howman-Giles;Russell C. Dale Pediatric Neurology 2010,

[9]

RESPONSE OF ANTI-NMDA RECEPTOR ENCEPHALITIS WITHOUT TUMOR TO IMMUNOTHERAPY INCLUDING RITUXIMAB[J] H Ishiura;S Matsuda;M Higashihara;M Hasegawa;A Hida;R Hanajima;T Yamamoto;J Shimizu;J Dalmau;S Tsuji Neurology 2008,

[10]

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies[J] Josep Dalmau;Amy J Gleichman;Ethan G Hughes;Jeffrey E Rossi;Xiaoyu Peng;Meizan Lai;Scott K Dessain;Myrna R Rosenfeld;Rita Balice-Gordon;David R Lynch Lancet Neurology 2008,

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