颈动脉内-中膜厚度及粥样硬化斑块与冠心病的相关性研究

被引：11

作者：

包艳娟

陈小伟

邵永富

魏敏

机构：

[1] 襄阳市中心医院影像科

来源：

中华临床医师杂志(电子版) | 2011年 / 5卷 / 10期

关键词：

冠状动脉狭窄; 颈动脉; 内-中膜厚度; 动脉粥样硬化斑块;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

100201 [内科学];

摘要：

目的探讨冠心病(CAD)患者颈动脉内-中膜厚度(IMT)及粥样硬化斑块与冠状动脉粥样硬化狭窄的相关性。方法以98例行冠脉造影的患者为研究对象,冠状动脉狭窄≥50%者57例为CAD组,冠状动脉狭窄<50%者41例为对照组,并进行Gensini积分。所有患者均行双侧颈动脉超声检查,检测颈动脉IMT及粥样硬化斑块Crouse积分,并与冠状动脉Gensini积分行相关性分析。结果 CAD组多支病变、单支病变亚组及对照组冠状动脉Gensini积分分别为42.65±4.33、24.70±2.29和15.36±3.06,颈动脉IMT分别为(1.37±0.16)mm、(1.21±0.14)mm和(0.92±0.11)mm,颈动脉粥样硬化斑块Crouse积分分别为2.05±0.17、1.29±0.18和0.36±0.05,三组间差异有统计学意义(P<0.05)。颈动脉IMT及粥样斑块Crouse积分与冠状动脉Gensini积分呈正相关。结论颈动脉IMT及粥样斑块与冠状动脉粥样硬化狭窄密切相关。高频超声能早期发现颈动脉内-中膜增厚及粥样硬化斑块,对有效预防CAD的发生有重要意义,可作为冠状动脉病变预测的一种较好的检查方法。

引用

页码：2998 / 3001

页数：4

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