幽门螺杆菌CagA及VacA致病机制的研究进展

被引：63

作者：

涂宏飞 ^{[1
]}

费素娟 ^{[2
]}

机构：

[1] 徐州医科大学

[2] 徐州医科大学附属医院消化内科

来源：

中国中西医结合消化杂志 | 2019年 / 27卷 / 05期

关键词：

幽门螺杆菌; CagA; VacA; 致病机制;

D O I：

暂无

中图分类号：

R573 [胃疾病];

学科分类号：

100201 [内科学];

摘要：

<正>幽门螺杆菌是世界上感染率最高的细菌之一[1]。虽然在世界许多地区幽门螺杆菌的感染率较前有所下降,但世界上仍有近一半的人口受到幽门螺杆菌的影响[2]。大多数感染幽门螺杆菌的人没有明显的临床症状,然而幽门螺杆菌是与消化系统疾病发展相关的一个重要因素。据统计,大约不到0.01%的幽门螺杆菌感染者发展为胃黏膜相关淋巴组织淋巴瘤（MALT）,0.1%～3%发展为胃癌,1%～10%发展为消化性溃疡,高达10%～15%将发展为幽门螺杆菌相关疾病[3]

引用

页码：399 / 402

页数：4

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