心肌肌钙蛋白的研究进展

被引:11
作者
张海霞
机构
[1] 天津市胸科医院检验科
关键词
心肌肌钙蛋白; 高灵敏度; 进展;
D O I
10.13602/j.cnki.jcls.2012.03.029
中图分类号
R540.4 [诊断学];
学科分类号
100201 [内科学];
摘要
作为检测心肌细胞损伤的一项灵敏而特异的指标,心肌肌钙蛋白(cardiac troponin,cTn)是目前诊断心肌损伤尤其是AMI的重要生物学标志物。近年来,随着检测技术的迅速发展,cTn分析性能大大提高,已广泛用于心肌缺血检测,AMI早期诊断,不良心脏事件预测,急性冠脉综合征危险分层,治疗药物监测,普通人群结构性心脏疾病、死亡风险判断,老年人群心力衰竭及心血管事件死亡风险相关性分析,老年心力衰竭患者预后预测及血透析患者预后判断等。尽管cTn的检测与临床应用方面仍有许多问题需待解决,但随着cTn检测能力、分析性能的提高及病理生理机制的深入研究,这将有助于改善临床患者的诊断、治疗和预后。
引用
收藏
页码:216 / 218
页数:3
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