运动性与病理性心肌肥大左室肌球蛋白α和β重链变化比较

被引：15

作者：

李昭波

高云秋

庞永正

刘秀华

唐朝枢

机构：

[1] 北京医科大学

[2] 北京医科大学北京

来源：

体育科学 | 1997年 / 01期

关键词：

运动; 肌球蛋白重链; 心肌肥大;

D O I：

暂无

中图分类号：

G804.7 [运动生物化学];

学科分类号：

摘要：

对大鼠运动心肌肥大和病理心肌肥大模型心室肌球蛋白α和β重链的变化进行比较研究,结果发现大鼠经10周游泳训练后引起心肌肥大,心室肌球蛋白α重链百分比和肌原纤维ATPase活性升高,β重链百分比降低(p<0.05)。与此变化相反,自发性高血压大鼠和由异丙肾上腺素诱导的心肌肥大大鼠心室肌球蛋α重链百分比和肌纤维ATPase活性降低,β重链百分比升高(P<0.05)。说明运动心脏的重塑过程不同于病理性心脏,前者重塑后使心肌收缩性提高,后者重塑后心脏功能降低。

引用

页码：50 / 53

页数：4

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