EFFECTS OF ACUPUNCTURE ON THE LEVELS OF ENDOTHELIN,TXB2,AND 6-Keto-PGF1a IN APOPLEXY PATIENTS

In order to delve into the mechanism governing the treatment of apoplexy byacupuncture at yangming channel points as main points,we observed the changes inthe endothelin(ET)level in plasma,TXB2and 6-Keto-PGF1αlevels in urine inconvalescent apoplexy patients during acupuncture treatment.The results showed thatthe ET level in plasma in convalescent apoplexy patients was significantly higher thanthat in healthy subjects(P<0.05),and the ET level in plasma in patients was decreasedafter one course of acupuncture treatment.It was found that before treatment theTXB2level in urine in apoplexy patients was significantly higher than in healthysubjects,and the 6-Keto-PGF1αlevel in urine in the patients was significantly lowerthan that in healthy subjects,with an increased ratio of TXB2to 6-Keto-PGF1α.Afteracupuncture treatment,the TXB2level in urine was lowered with a decrease in theratio of TXB2to 6-Keto-PGF1α.All this indicated that one of the mechanismsgoverning acupuncture treatment of apoplexy acupuncture at yangming channelpoints as main points was that acupuncture could produce therapeutic effects byadjusting the imbalance of important vaso-active substances,ET,TXA2,and PGI2.