罗比卡因硬膜外腔阻滞在分娩镇痛中的应用

被引:9
作者
吕安祺
王珊娟
杭燕南
林建华
机构
[1] 上海第二医科大学附属仁济医院麻醉科
[2] 上海第二医科大学附属仁济医院妇产科
关键词
分娩镇痛; 硬膜外腔阻滞; 罗比卡因; 布比卡因;
D O I
暂无
中图分类号
R614.42 [];
学科分类号
100217 ;
摘要
目的 观察不同浓度罗比卡因应用于分娩镇痛的安全性与有效性 ,并与布比卡因进行比较。方法 选择足月、单胎、头位初产妇 88例 ,ASAⅠ~Ⅱ级 ,其中自愿接受分娩镇痛 48例 ,随机分为四组 (n =12 ) :(1) 0 2 %布比卡因 (B组 ) ;(2 ) 0 2 %罗比卡因 (R组 ) ;(3) 0 1%罗比卡因 +芬太尼 2 μg/ml间断注药 (RF组 ) ;(4) 0 1%罗比卡因 +芬太尼 2 μg/ml持续用药 (RFC组 )。对照组 40例未行分娩镇痛。于产程进展宫口开至 3cm时 ,行硬膜外腔穿刺置管 ,首次剂量 8~ 12ml。B组、R组和RF组按需追加 5~ 8ml/次 ,RFC组在给首量后半小时 ,用输液泵将维持量以 5~ 7ml/h持续硬膜外腔输注至宫口开全停药。结果 行分娩镇痛各组产妇用药后VAS评分均明显降低 ,感觉减退平面均在T10 以下 (T10 ~S4 ) ,Bromage评分均为 0级。罗比卡因各组宫口扩张速率和胎头下降速率较快。对产程和分娩方式和母胎均无明显影响。联合用药可减少局麻药用量。结论 罗比卡因应用于分娩镇痛对产程影响较小 ,联合用药更加优越 ,持续输注实施简便
引用
收藏
页码:243 / 245
页数:3
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