噻托溴铵治疗慢性阻塞性肺病的进展

被引:9
作者
任振义 [1 ]
白春学 [2 ]
机构
[1] 杭州市第一人民医院
[2] 复旦大学附属中山医院
关键词
噻托澳铵; 慢性阻塞性肺病; M受体阻滞剂;
D O I
暂无
中图分类号
R563.9 [其他];
学科分类号
1002 ; 100201 ;
摘要
噻托溴铵(tiotropium bromide)是一个新型的治疗慢性阻塞性肺病(COPD)的吸入型支气管扩张药物,通过与M3受体结合阻滞乙酰胆碱的作用从而缓解支气管平滑肌的痉挛,吸入一次疗效持续24h以上。临床试验结果表明该药对中重度COPD具有良好疗效,在改善呼吸困难、生活质量、减少住院次数方面优于沙美特罗,噻托溴铵qd对支气管的舒张作用明显好于溴化异丙托品qid和沙美特罗bid,且能改善通气功能和肺容积,耐受性和安全性较好。主要不良反应为口干。
引用
收藏
页码:673 / 676
页数:4
相关论文
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