自转运蛋白作为细菌表面展示系统的研究进展

被引:3
作者
刘艳如 [1 ,2 ,3 ]
王作镇 [1 ,2 ,3 ]
赵丙春 [1 ,2 ,3 ]
黄建忠 [1 ,2 ,3 ]
朱晓兰 [1 ,2 ,3 ]
邱黎清 [1 ,2 ,3 ]
舒正玉 [1 ,2 ,3 ]
机构
[1] 福建师范大学工业微生物发酵技术国家地方联合工程研究中心
[2] 福建师范大学教育部工业微生物工程中心
[3] 福建师范大学生命科学学院
关键词
自转运蛋白; V型分泌途径; 细菌表面展示;
D O I
10.13488/j.smhx.20150310
中图分类号
Q932 [微生物细胞学];
学科分类号
071009 ;
摘要
细菌表面展示技术已成功应用于生物技术、生物医药等诸多领域。在众多细菌表面展示系统中,基于自转运蛋白构建的细菌表面展示系统因其强大的外源蛋白展示能力,展现出良好的应用潜力和应用前景。本文综述了当前已发现的自转运蛋白的种类、已解析的自转运蛋白的结构及其分泌过程,概述了基于自转运蛋白构建的细菌表面展示系统的优点及其应用情况。
引用
收藏
页码:357 / 364
页数:8
相关论文
共 17 条
[1]   细菌脂肪酶在大肠杆菌细胞表面的功能性展示 [J].
徐丽香 ;
王作镇 ;
舒正玉 ;
武海龙 ;
刘艳如 ;
李欣 ;
黄建忠 .
生物技术通报, 2014, (06) :192-198
[2]  
Crystal structure of the transport unit of the autotransporter adhesin involved in diffuse adherence from Escherichia coli[J] . Iris Gawarzewski,Frank DiMaio,Elisa Winterer,Britta Tschapek,Sander H.J. Smits,Joachim Jose,Lutz Schmitt.Journal of Structural Biology . 2014
[3]   Surface display of the HPV L1 capsid protein by the autotransporter Shigella IcsA [J].
Xu, Dan ;
Yang, Xiaofeng ;
Wang, Depu ;
Yu, Jun ;
Wang, Yili .
JOURNAL OF MICROBIOLOGY, 2014, 52 (01) :77-82
[4]   Autodisplay of nitrilase from Klebsiella pneumoniae and whole-cell degradation of oxynil herbicides and related compounds [J].
Detzel, Christian ;
Maas, Ruth ;
Tubeleviciute, Agne ;
Jose, Joachim .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2013, 97 (11) :4887-4896
[5]   VirK Is a Periplasmic Protein Required for Efficient Secretion of Plasmid-Encoded Toxin from Enteroaggregative Escherichia coli [J].
Tapia-Pastrana, Gabriela ;
Chavez-Duenas, Lucia ;
Lanz-Mendoza, Humberto ;
Teter, Ken ;
Navarro-Garcia, Fernando .
INFECTION AND IMMUNITY, 2012, 80 (07) :2276-2285
[6]   Cell surface display of a β-glucosidase employing the type V secretion system on ethanologenic Escherichia coli for the fermentation of cellobiose to ethanol [J].
Munoz-Gutierrez, Ivan ;
Oropeza, Ricardo ;
Gosset, Guillermo ;
Martinez, Alfredo .
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2012, 39 (08) :1141-1152
[7]  
Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors[J] . European Journal of Pharmaceutical Sciences . 2010 (1)
[8]   High-throughput Sorting of an Anticalin Library via EspP-mediated Functional Display on the Escherichia coli Cell Surface [J].
Binder, Uli ;
Matschiner, Gabriele ;
Theobald, Ina ;
Skerra, Arne .
JOURNAL OF MOLECULAR BIOLOGY, 2010, 400 (04) :783-802
[9]   Crystal Structure of a Full-Length Autotransporter [J].
van den Berg, Bert .
JOURNAL OF MOLECULAR BIOLOGY, 2010, 396 (03) :627-633
[10]   Functional display of Pseudomonas and Burkholderia lipases using a translocator domain of EstA autotransporter on the cell surface of Escherichia coli [J].
Yang, Taek Ho ;
Kwon, Min-A. ;
Song, Jae Kwang ;
Pan, Jae Gu ;
Rhee, Joon Shick .
JOURNAL OF BIOTECHNOLOGY, 2010, 146 (03) :126-129