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Univ Manchester, Salford Royal Hosp, Dept GI Sci, Sch Translat Med Gastrointestinal Sci,Manchester, Salford M6 8HD, Lancs, England Univ Manchester, Salford Royal Hosp, Dept GI Sci, Sch Translat Med Gastrointestinal Sci,Manchester, Salford M6 8HD, Lancs, England