电针治疗膝骨关节炎的基础研究进展

被引：21

作者：

马永圆

郭海云

白福海

李雨衡

张明

邓姣

熊利泽

机构：

[1] 中国人民解放军空军军医大学西京医院

来源：

上海针灸杂志 | 2018年 / 37卷 / 07期

基金：

国家自然科学基金重大项目;

关键词：

骨关节炎,膝关节; 电针; 动物模型; 综述; 针刺疗法;

D O I：

暂无

中图分类号：

R246.9 [其他];

学科分类号：

100231 [临床病理学];

摘要：

中国膝骨关节炎(knee osteoarthritis,KOA)整体患病率为8.1%,60岁以上人群高达49%。KOA可由创伤、炎症、退行性病变等多种因素引起,目前尚无修复关节损伤的有效方法。临床治疗的首要目标在于阻止疾病进展、缓解疼痛、保护关节功能并改善患者生活质量。目前电针已广泛应用于KOA的临床治疗,并取得较好疗效,然而其作用机制仍不清楚,具体治疗措施缺乏标准。而用于基础研究的动物模型与电针治疗方法种类繁复,难以综合进行客观评价,影响了机制的深入研究,对于临床实践的支撑作用很弱。该文从KOA模型构建、电针治疗策略和治疗机制3个方面对电针治疗KOA实验研究进行综述,为研究者在动物模型、电针策略选择和机制研究方面提供参考。

引用

页码：833 / 840

页数：8

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