糖尿病性视网膜病变分子机制的研究进展

被引：5

作者：

崔彦

许迅

机构：

[1] 上海市第一人民医院眼科

来源：

眼视光学杂志 | 2007年 / 02期

关键词：

糖尿病/并发症; 糖尿病视网膜病变/病因学; 分子生物学; 生物化学;

D O I：

暂无

中图分类号：

R774.1 [视网膜疾病];

学科分类号：

摘要：

糖尿病性视网膜病变是发达国家首位的致盲原因,慢性高血糖是其主要原因。对于高血糖导致糖尿病性视网膜病变的生化和分子机制,目前有五种假说:多元醇途径的增加、终末糖基化产物的增加、蛋白激酶C的激活、增加的己糖胺途径以及线粒体活性氧产生增多。本文对各途径的分子机制研究进展予以综述,并分析各途径间的相互关联及将来的研究方向。

引用

页码：135 / 138

页数：4

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