骨碎补总黄酮对骨质疏松症患者牙槽骨的影响

被引:9
作者
杨锋 [1 ,2 ]
孙玉华 [1 ,2 ]
吕中静 [1 ,2 ]
刘佃滨 [1 ]
秦莹 [1 ,2 ]
肖丽婷 [1 ,2 ]
孙晋虎 [1 ,2 ]
机构
[1] 徐州医科大学口腔医学院
[2] 徐州医科大学附属医院口腔科
关键词
骨碎补总黄酮; 骨质疏松症; 牙槽骨; 骨密度;
D O I
暂无
中图分类号
R782.1 [牙及牙槽骨外科];
学科分类号
100210 [外科学];
摘要
目的 :研究骨碎补总黄酮对合并牙列缺损或缺失的骨质疏松症患者牙槽骨高度、厚度、骨密度及牙槽嵴顶宽度的影响。方法:将符合纳入标准的46例患者随机分为实验组和对照组,每组23例,实验组服用强骨胶囊,对照组服用阿仑膦酸钠片;于药物治疗前及治疗后1、3、6个月时分别行锥形束CT(CBCT)检查,应用Anatomage invivo 5软件测量并观察牙槽骨高度、厚度、骨密度及牙槽嵴顶宽度的变化,采用SPSS17.0软件包进行统计学分析。结果:对照组牙槽骨颊(唇)侧皮质骨的骨密度在药物治疗后1个月时较实验组显著升高(P<0.05),实验组牙槽骨的颊(唇)侧皮质骨骨密度在药物治疗后3个月和6个月时均较对照组显著升高(P<0.05)。对照组牙槽嵴顶宽度和牙槽骨的颊(唇)侧皮质骨厚度在药物治疗后3个月较实验组显著升高(P<0.05),在药物治疗后6个月时,2组间差异无统计学意义(P>0.05)。不同时点实验组和对照组在基骨的颊(唇)侧皮质骨、松质骨、腭(舌)侧皮质骨的厚度变化均无显著差异(P>0.05)。结论 :骨碎补总黄酮能显著增加骨质疏松症患者牙槽骨骨密度,在增加牙槽骨的颊(唇)侧皮质骨的骨密度上较阿仑膦酸钠存在优势;骨碎补总黄酮能增加骨质疏松症患者牙槽骨的颊(唇)侧皮质骨厚度,对牙槽嵴顶宽度、牙槽骨高度影响不大。
引用
收藏
页码:34 / 40
页数:7
相关论文
共 21 条
[1]
Clinician's Guide to Prevention and Treatment of Osteoporosis [J].
Cosman, F. ;
de Beur, S. J. ;
LeBoff, M. S. ;
Lewiecki, E. M. ;
Tanner, B. ;
Randall, S. ;
Lindsay, R. .
OSTEOPOROSIS INTERNATIONAL, 2014, 25 (10) :2359-2381
[2]
European guidance for the diagnosis and management of osteoporosis in postmenopausal women [J].
Kanis, J. A. ;
McCloskey, E. V. ;
Johansson, H. ;
Cooper, C. ;
Rizzoli, R. ;
Reginster, J. -Y. .
OSTEOPOROSIS INTERNATIONAL, 2013, 24 (01) :23-57
[3]
Bisphosphonates and their clinical implications in endodontic therapy.[J].A.‐T. Moinzadeh;H. Shemesh;N. A. M. Neirynck;C. Aubert;P. R. Wesselink.Int Endod J.2012, 5
[4]
Surgical Technique: Transfer of the Anterior Portion of the Gluteus Maximus Muscle for Abductor Deficiency of the Hip [J].
Whiteside, Leo A. .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2012, 470 (02) :503-510
[5]
Phytochemical Characteristics; Free Radical Scavenging Activities; and Neuroprotection of Five Medicinal Plant Extracts.[J].Chia Lin Chang;Che San Lin;Guia Hung Lai;Ann Gill Taylor.Evidence-Based Complementary and Alternative Medicine.2011,
[6]
Relationship between the bone density estimated by cone‐beam computed tomography and the primary stability of dental implants.[J].Kei Isoda;Yasunori Ayukawa;Yoshihiro Tsukiyama;Motofumi Sogo;Yasuyuki Matsushita;Kiyoshi Koyano.Clinical Oral Implants Research.2011, 7
[7]
Traditional Chinese medicines and bone formation - A review [J].
Wong, RWK ;
Rabie, ABM .
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2006, 64 (05) :828-837
[8]
Visual assessment of the mandibular cortex on panoramic radiographs to identify postmenopausal women with low bone mineral densities [J].
Lee, K ;
Taguchi, A ;
Ishii, K ;
Suei, Y ;
Fujita, M ;
Nakamoto, T ;
Ohtsuka, M ;
Sanada, M ;
Tsuda, M ;
Ohama, K ;
Tanimoto, K ;
White, SC .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 2005, 100 (02) :226-231
[9]
Effects of ovariectomy on trabecular structures of rat alveolar bone [J].
Tanaka, M ;
Ejiri, S ;
Toyooka, E ;
Kohno, S ;
Ozawa, H .
JOURNAL OF PERIODONTAL RESEARCH, 2002, 37 (02) :161-165
[10]
强骨胶囊治疗原发性骨质疏松症基础研究进展 [J].
申浩 ;
谢雁鸣 .
中国中医基础医学杂志, 2012, 18 (12) :1402-1404