脓毒症与凝血功能异常

被引：20

作者：

戴林峰

王醒

机构：

[1] 南京中医药大学第一临床医学院

来源：

东南大学学报(医学版) | 2012年 / 31卷 / 03期

关键词：

脓毒症; 凝血机制; 凝血因子; 文献综述;

D O I：

暂无

中图分类号：

R459.7 [急症、急救处理];

学科分类号：

100231 [临床病理学];

摘要：

凝血功能异常是急危重症患者常见的并发症。脓毒症时,组织因子诱导的外源性凝血途径激活,凝血机制增强,抗凝机制和纤溶系统受抑制,导致微循环血栓形成,器官微循环紊乱而加重器官功能障碍,与死亡率升高密切相关。多种炎症介质参与凝血机制的启动,在炎症过程中也经常有许多凝血蛋白的参与。作者以急危重症患者普遍存在凝血功能障碍为基础,探讨脓毒症时炎症反应和凝血机制之间的关系。

引用

页码：359 / 362

页数：4

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