TNF-α、IL-6在炎症性肠病发病机制中的研究进展

被引:66
作者
唐齐林 [1 ]
周国华 [2 ]
王为 [2 ]
机构
[1] 南华大学附属南华医院消化内科
[2] 解放军第一六九医院消化内科
关键词
肿瘤坏死因子α; 白细胞介素6; 炎性肠病;
D O I
暂无
中图分类号
R574.53 [回肠疾病];
学科分类号
100201 [内科学];
摘要
炎症性肠病是一类病因不明的胃肠道慢性非特异性炎症,其发病过程是包括多种细胞因子在内的自身免疫的异常,最终导致组织的损伤,属于自身免疫性疾病的一种,其中肠道免疫系统调节异常在其发病机制中起着极其重要的作用,而作为重要的促炎因子和免疫调节因子肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)在炎症性肠病的发病过程中参与炎症的发生以及信号的转导。该文就近年来TNF-α、IL-6在炎症性肠病发病机制中的研究予以综述。
引用
收藏
页码:1174 / 1176
页数:3
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