创伤性脑损伤后认知障碍研究现状

被引:27
作者
任丽华 [1 ]
顼红宇 [2 ]
贺晓生 [3 ]
机构
[1] 北京军区白求恩国际和平医院神经外科
[2] 第四军医大学空军医学系
[3] 第四军医大学西京医院神经外科
关键词
TBI; 认知障碍; 神经功能康复;
D O I
暂无
中图分类号
R651.15 [];
学科分类号
摘要
<正>创伤性脑损伤(traumatic brain injury,TBI)具有较高的发生率,尤其是在当代社会工业和经济高度发达的社会中。TBI后遗症多,残、死率高,不仅给患者本人及其家庭带来了巨大痛苦,也对社会造成了沉重的负担。TBI的严重后果包括:①运动功能缺陷;②知觉障碍;③认知缺陷;④语言障碍;⑤人格改变等。认知障碍为TBI最常见、最持久的后遗症状之一。本文就TBI后认知障碍的研究现状进行简要概述。一、脑损伤后认知障碍的发生机制研究
引用
收藏
页码:94 / 96
页数:3
相关论文
共 11 条
[1]
Preclinical Assessment for Selectively Disrupting a Traumatic Memory via Postretrieval Inhibition of Glucocorticoid Receptors [J].
Taubenfeld, Stephen M. ;
Riceberg, Justin S. ;
New, Antonia S. ;
Alberini, Cristina M. .
BIOLOGICAL PSYCHIATRY, 2009, 65 (03) :249-257
[2]
Persistent disruption of a traumatic memory by postretrieval inactivation of glucocorticoid receptors in the amygdala [J].
Tronel, Sophie ;
Alberini, Cristina M. .
BIOLOGICAL PSYCHIATRY, 2007, 62 (01) :33-39
[3]
Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: A putative post-traumatic stress disorder model [J].
Kohda, K. ;
Harada, K. ;
Kato, K. ;
Hoshino, A. ;
Motohashi, J. ;
Yamaji, T. ;
Morinobu, S. ;
Matsuoka, N. ;
Kato, N. .
NEUROSCIENCE, 2007, 148 (01) :22-33
[4]
Age-dependent effects of serotonin-1A receptor gene deletion in spatial learning abilities in mice.[J].Mathieu Wolff;Pierre Costet;Cornelius Gross;René Hen;Louis Segu;Marie-Christine Buhot.Molecular Brain Research.2004, 1
[5]
S100B is increased in mood disorders and may be reduced by antidepressive treatment [J].
Schroeter, ML ;
Abdul-Khaliq, H ;
Diefenbacher, A ;
Blasig, IE .
NEUROREPORT, 2002, 13 (13) :1675-1678
[6]
Role of adrenal stress hormones in forming lasting memories in the brain [J].
McGaugh, JL ;
Roozendaal, B .
CURRENT OPINION IN NEUROBIOLOGY, 2002, 12 (02) :205-210
[7]
Early S-100B serum level correlates to quality of life in patients after severe head injury [J].
Woertgen, C ;
Rothoerl, RD ;
Brawanski, A .
BRAIN INJURY, 2002, 16 (09) :807-816
[8]
Mild Head Injury in Sports.[J].Robert A. Ruchinskas;Joseph P. Francis;Jeffrey T. Barth.Applied Neuropsychology.1997, 1
[9]
脑外伤患者的认知功能训练 [J].
贺旭 ;
洪军 ;
林建华 .
中国临床康复, 2002, (20) :3086-3087
[10]
神经心理障碍健康教育与脑损伤康复的探讨 [J].
卢淑金 ;
磨飞鸿 .
医学文选, 2002, (02) :263-264