NT-pro-BNP在治疗ACS中的应用和意义

被引:9
作者
傅燕琳
机构
[1] 复旦大学附属中山医院上海市心血管病研究所
关键词
BNP; NT-pro-BNP; ACS;
D O I
10.14163/j.cnki.11-5547/r.2010.04.081
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
1002 ; 100201 ;
摘要
脑钠肽(BNP)是一种由心脏分泌的神经内分泌激素,最早被发现在心室壁压力增加时大量分泌,因而在诊断治疗心衰、判断心衰患者预后中广泛被应用。近来的研究认为BNP在冠心病领域中也有重大的应用意义。在血液中检测BNP水平的变化能独立、有效、敏感地判断ACS(急性冠脉综合征)患者短期和长期的预后,并且能指导治疗方法的选择,判断疗效。NT-pro-BNP(N末端脑钠肽前体)与BNP有相似的生理功能,但前者较后者在临床应用中更具有优点,因而逐渐取代后者。
引用
收藏
页码:55 / 57
页数:3
相关论文
共 11 条
[1]  
BNP or NTproBNP a clinician‘s perspective. Johannes Steiner,,Maya Guglin. International Journal of Cardiology . 2008
[2]  
Prognostic value of serum biomarkers in association with TIMI risk score for acute coronary syndromes. EULER R.F.MANENTI. Clinical Cardiology . 2006
[3]  
Journal of the American College of Cardiolo-gy . 2004
[4]  
N-terminal pro-brain natriuretic peptide in relation to inflammation,myocardial necrosis,and the effect of an invasive strategy in unstable coronary artery disease. Rudolf Jarai. Journal of the American College of Cardiology . 2003
[5]  
Pathophysiology, prognostic significance and clinical utility of B-type natriuretic peptide in acute coronary syndromes. Wiviott SD,de Lemos JA,Morrow DA. Clinica Chimica Acta . 2004
[6]  
B-type natriuretic peptide in cardiovascular disease. de-Lemos JA,McGuire DK,Drazner MH,et al. Lancet,The . 2003
[7]  
N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary artery disease: a Global Utilization of Strategies To Open occluded arteries (. James SK,Lindahl B,Siegbahn A,et al. Circulation . 2003
[8]  
N-Terminal Pro-Brain Natriuretic Peptide and Other Risk Markers for the Separate Prediction of Mortality and Subsequent Myocardial Infarction in Patients With Unstable Coronary Artery Disease: A Global Utilization of Strategies To Open occluded arteries (GUSTO)-IV Substudy[J] . Stefan K James,Bertil Lindahl,Agneta Siegbahn,Mats Stridsberg,Per Venge,Paul Armstrong,Elliot S Barnathan,Robert Califf,Eric J Topol,Maarten L Simoons,Lars Wallentin. &nbspCirculation . 2003 (3)
[9]  
Pathophysiology, prognostic significance and clinical utility of B-type natriuretic peptide in acute coronary syndromes[J] . Stephen D Wiviott,James A de Lemos,David A Morrow. &nbspClinica Chimica Acta . 2004 (2)
[10]   B-type natriuretic peptide in cardiovascular disease [J].
de Lemos, JA ;
McGuire, DK ;
Drazner, MH .
LANCET, 2003, 362 (9380) :316-322