亚低温对局灶脑缺血再灌注损伤作用的实验研究

被引:2
作者
黄峰平
周良辅
机构
[1] 上海医科大学华山医院神经外科
关键词
脑缺血; 再灌注损伤; 亚低温;
D O I
暂无
中图分类号
R741 [神经病学];
学科分类号
1002 ;
摘要
用改良Koizumi's局灶脑缺血模型,对比研究了常温、缺血期亚低温、再灌注期亚低温、缺血期加再灌注期亚低温对局部脑血流、血脑屏障及缺血梗塞灶体积影响。发现缺血期加再灌注期及单纯缺血期亚低温均有改善缺血周边区再灌注后急性高灌注和继发低灌流及核心区持续低灌流、减轻血脑屏障破坏、减少缺血梗塞灶体积的作用,该作用尤以前者为明显。
引用
收藏
页码:63 / 67+84 +84
页数:6
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