美金刚与血管性痴呆

被引:6
作者
任永富
刘合玉
机构
[1] 郑州大学第二附属医院神经康复科
关键词
美金刚; 血管性痴呆; NMDA受体;
D O I
暂无
中图分类号
R749.13 [];
学科分类号
摘要
兴奋性氨基酸毒性是血管性痴呆的发病机制之一,谷氨酸是脑内主要的兴奋性神经递质。美金刚是一种中等亲和力、非竞争性、电压依赖性N-甲基-D-天冬氨酸(NMDA)受体阻滞剂,能够阻断NMDA受体介导的胞内Ca2+超载,避免兴奋性毒性,可用于血管性痴呆的治疗。
引用
收藏
页码:289 / 292
相关论文
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