动脉内溶栓后低分子肝素治疗急性脑梗死11例

被引:2
作者
于顾然
王永生
姜亚军
机构
[1] 江苏省中医院脑病中心,江苏省中医院脑病中心,江苏省中医院脑病中心南京,南京,南京
关键词
脑梗塞; 血栓溶解疗法; 肝素; 低分子量;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
目的观察急诊动脉内溶栓加低分子肝素治疗急性脑梗死的疗效及预后。方法对11例治疗时间窗在6h内的急性脑梗死患者行动脉内溶栓治疗。术前及术后24h均行神经功能评价(美国国立卫生研究院卒中量表,NIHSS)。术后根据急性心肌梗死溶栓标准灌注分级(TIMI)评价血管再通程度。溶栓后20d,皮下注射低分子肝素钙5000U。20d后,根据改良的Rank分数法(MRS)评价独立生活能力。结果溶栓前,患者NIHSS评分平均为17±8,术后24h为10±9,溶栓前后比较差异有显著意义(P<0.05)。24h神经功能评价,7例改善,4例无改善,差异有显著意义(P<0.05)。溶栓后7例患者完全再通,1例部分再通,3例未再通。MRS评分,8例患者疗效良好,3例疗效差,其中1例死亡。结论急诊动脉内溶栓是安全、可行的,溶栓后24h神经功能检查改善程度与20d后临床疗效密切相关,用低分子肝素作为溶栓后续治疗安全有效。
引用
收藏
页码:156 / 159
页数:4
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