神经节苷脂GD3在神经系统中的作用及机制附视频

被引：5

作者：

杨瑞瑞 ^{[1
]}

胡清韵 ^{[2
]}

邓宇斌 ^{[1
]}

机构：

[1] 中山大学附属第一医院转化医学中心

[2] 中山大学中山医学院

来源：

脑与神经疾病杂志 | 2016年 / 09期

基金：

广东省自然科学基金;

关键词：

神经节苷脂; GD3; 小鼠; NSC; 神经元; 神经鞘脂; 小家鼠; 神经组织; 神经系统; 脂筏;

D O I：

暂无

中图分类号：

R338 [神经生理学];

学科分类号：

0710 ; 071006 ;

摘要：

<正>神经节苷脂(ganglioside,GS)是一组含有唾液酸糖鞘脂,由亲水的含唾液酸的寡糖链和疏水的神经酞胺组成。在脊椎动物各组织的细胞膜上广泛存在,尤其以中枢神经系统中含量最高[1]。目前已分离鉴定出70余种GS,神经节苷脂的命名通常采用Svennerholm命名法[2]。大写字母"G"代表神经节苷脂,紧接着的字母"M、D、T、Q、P、H或S"则代表1～7个唾液酸的数量;用5减糖基数之差标示含相同数量唾液酸但不同糖基数的神经节苷脂,如1表示4个糖基,2表示3

引用

页码：585 / 588

页数：4

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