冠状动脉钙化和CT血管造影与常规危险因素诊断和预测冠心病的对比研究

被引：30

作者：

吕滨

庄囡

戴汝平

蒋世良

Matthew J.Budoff

机构：

[1] 中国医学科学院中国协和医科大学阜外心血管病医院放射科,通用电气(中国)有限公司-医疗集团系统,中国医学科学院中国协和医科大学阜外心血管病医院放射科,中国医学科学院中国协和医科大学阜外心血管病医院放射科,美国加州大学洛杉矶分校圣约翰心血管病研究中心北京,北京,北京

来源：

中华心血管病杂志 | 2004年 / 06期

关键词：

冠状动脉疾病; 冠状血管造影术; 危险因素; 钙质沉着症;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

目的　对比冠状动脉钙化积分 (CCS)、电子束CT血管造影 (EBA)与常规冠心病危险因素诊断和预测冠心病 (一支以上冠状动脉狭窄率≥ 5 0 % )的价值。方法　 10 7例患者同时行常规冠状动脉造影 (CAG)、电子束CT冠状动脉钙化 (非增强扫描 )和电子束CT血管造影 (增强扫描 ) ,以及常规冠心病危险因素分析。EBA采用静脉法单层心电门控增强扫描 ,诊断在断层和三维重建图像上完成。CCS采用Agatston方法完成。电子束CT及常规冠心病危险因素与CAG结果做双盲法对照研究。结果　本组冠心病患者和非冠心病患者分别为 6 5例 ( 6 0 7% )和 4 2例 ( 39 3% ) ,CCS在冠心病组和非冠心病组分别为 5 33 5± 6 0 6 5和 14 2 4± 2 93 6 (P <0 0 0 1)。年龄、体重指数、糖尿病和高胆固醇血症的发病率在冠心病组显著高于非冠心病组 (P <0 0 5 )。冠状动脉钙化阳性 (CCS >0 )诊断冠心病与EBA有相近的敏感性和阴性预测值 (P >0 0 5 )。EBA诊断非钙化性 (CCS =0 )或少量钙化(CCS <10 0 )冠状动脉节段狭窄的特异性和准确性高于CCS且差异有显著性 (P <0 0 1) ;但对于较多冠状动脉钙化病变 (CCS >10 0 )差异无显著性 (P >0 0 5 )。CCS和EBA诊断冠心病的敏感性和特异性分别为 79%和 73% (P >0 0 5 ) ,以及 6 6 %和 88% (P <0 0

引用

页码：15 / 19

页数：5

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