miRNA-21在前列腺癌中的作用

被引：3

作者：

刘四明

李刚

佟明

金艳阳

Sandeep Shrestha

机构：

[1] 辽宁医学院附属第一医院泌尿外科

来源：

天津医药 | 2011年 / 39卷 / 05期

关键词：

微RNAs; 前列腺肿瘤; 癌; 雄激素类; 受体,雄激素; 肿瘤标记,生物学; 肿瘤,激素依赖性; 综述;

D O I：

暂无

中图分类号：

R737.25 [前列腺肿瘤];

学科分类号：

100214 [肿瘤学];

摘要：

<正>前列腺癌是男性最常见的恶性肿瘤,在男性癌症相关致死性原因中居第2位[1]。手术治疗和放疗通常对临床局限性的前列腺癌有效,却对治疗转移性的前列腺癌效果欠佳。目前,去势手术治疗转移性前列腺癌是较常用方法,但大部分[2]

引用

页码：475 / 476

页数：2

共 8 条

[1]

The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer [J].

Ribas, Judit ;

Lupold, Shawn E. .

CELL CYCLE, 2010, 9 (05) :923-929

[2]

Androgen receptor abnormalities in castration-recurrent prostate cancer.[J].Nacusi;Tindall.Expert Review of Endocrinology & Metabolism.2009, 5

[3]

MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells [J].

Li, Tao ;

Li, Dong ;

Sha, Jianjun ;

Sun, Peng ;

Huang, Yiran .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 383 (03) :280-285

[4]

MicroRNA-21 is Overexpressed in Pancreatic Cancer and a Potential Predictor of Survival [J].

Dillhoff, Mary ;

Liu, James ;

Frankel, Wendy ;

Croce, Carlo ;

Bloomston, Mark .

JOURNAL OF GASTROINTESTINAL SURGERY, 2008, 12 (12) :2171-2176

[5]

Prostate cancer [J].

Damber, Jan-Erik ;

Aus, Gunnar .

LANCET, 2008, 371 (9625) :1710-1721

[6]

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.[J].Douglas D. Taylor;Cicek Gercel-Taylor.Gynecologic Oncology.2008, 1

[7]

miR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism [J].

Fujita, Shuji ;

Ito, Taiji ;

Mizutani, Taketoshi ;

Minoguchi, Shigeru ;

Yamamichi, Nlobutake ;

Sakurai, Kouhei ;

Iba, Hlideo .

JOURNAL OF MOLECULAR BIOLOGY, 2008, 378 (03) :492-504

[8]

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis [J].

Chang, Tsung-Cheng ;

Wentzel, Erik A. ;

Kent, Oliver A. ;

Ramachandran, Kalyani ;

Mullendore, Michael ;

Lee, Kwang Hyuck ;

Feldmann, Georg ;

Yamakuchi, Munekazu ;

Ferlito, Marcella ;

Lowenstein, Charles J. ;

Arking, Dan E. ;

Beer, Michael A. ;

Maitra, Anirban ;

Mendell, Joshua T. .

MOLECULAR CELL, 2007, 26 (05) :745-752

← 1 →