依托考昔在骨关节炎的治疗研究进展

被引:21
作者
王国春
机构
[1] 北京中日友好医院风湿免疫科
关键词
依托考昔; 骨关节炎; 研究进展;
D O I
暂无
中图分类号
R684.3 [关节炎];
学科分类号
100220 [骨科学];
摘要
非甾体抗炎药(NSAIDs,包括COX-2抑制剂)在骨关节炎(OA)的疾病管理中起着非常重要的作用,作为一种较新的COX-2抑制剂,依托考昔具有比传统NSAIDs更好的胃肠道安全性,其血药浓度达峰时间短、半衰期长等药理学特性,决定了其起效快和药效长。本文就依托考昔近些年发表的OA治疗相关随机对照研究、系统回顾研究和NNT研究等多个国内外文献进行回顾,并与其他NSAIDs的疗效和安全性进行比较分析,希望较全面总结依托考昔在OA疾病管理中的研究进展,为临床用药提供循证参考。
引用
收藏
页码:799 / 802
页数:4
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