肿瘤坏死因子-α及白介素在急性胰腺炎中的作用

被引：28

作者：

徐延钧 ^{[1
]}

吴新民 ^{[2
]}

郭亚民 ^{[2
]}

机构：

[1] 青海大学医学院研究生院

[2] 青海省人民医院普外科二病区

来源：

中国普外基础与临床杂志 | 2010年 / 17卷 / 09期

关键词：

急性胰腺炎; 细胞因子; 肿瘤坏死因子-α; 白介素;

D O I：

暂无

中图分类号：

R657.51 [];

学科分类号：

摘要：

目的总结急性胰腺炎(AP)时细胞因子网络的变化,各细胞因子的分类、相互作用及对全身的影响。方法复习近年来国内、外有关AP时细胞因子方面的文献并进行综述。结果 AP时细胞因子网络变化复杂,互相影响,存在各种调节机理。其中肿瘤坏死因子-α(TNF-α)及白介素类细胞因子在AP进展中起着重要作用。结论 AP时细胞因子的变化是一个复杂的过程,单独调节某个因子的释放对于治疗疾病本身并无明显效果,从免疫平衡角度考虑治疗应该是较好的研究方向。

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页码：993 / 996

页数：4

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