他汀类药物在心血管疾病中的临床应用与进展

被引：9

作者：

方振勤

机构：

[1] 天津市宝坻区海滨医院

来源：

医学理论与实践 | 2011年 / 24卷 / 07期

关键词：

他汀类药物; 多重效应; 心血管疾病;

D O I：

10.19381/j.issn.1001-7585.2011.07.009

中图分类号：

R54 [心脏、血管（循环系）疾病];

学科分类号：

1002 ; 100201 ;

摘要：

<正>所谓他汀类药物为一大类其英文词尾为statin(他汀)的药物的统称,在临床上主要用于调脂治疗,但应用他汀类药物的效应,远非单独由于血脂水平变化引起。他汀类药物除降脂作用外,还具有多重作用,包括保护内皮、抗炎、抗氧化应激、抗增殖、抑

引用

页码：760 / 762

页数：3

共 11 条

[1] 经皮冠状动脉介入治疗中无复流发生机制及评价方法 [J].

王红 ;

黄岚 .

中国微循环, 2005, (06) :449-452

[2] 辛伐他汀治疗颈动脉粥样硬化疗效观察 [J].

陈杭军 ;

余毅 ;

林雪香 .

中国实用内科杂志, 2005, (07) :621-622

[3]

Atorvastatin Prevents Angiotensin II–Induced Vascular Remodeling and Oxidative Stress[J] . Ana M. Briones,Natalia Rodríguez-Criado,Raquel Hernanz,Ana B. García-Redondo,Raul R. Rodrigues-Díez,María J. Alonso,Jesús Egido,Marta Ruiz-Ortega,Mercedes Salaices.Hypertension . 2009 (1)

[4]

Evidence for Statin Pleiotropy in Humans: Differential Effects of Statins and Ezetimibe on Rho-Associated Coiled-Coil Containing Protein Kinase Activity, Endothelial Function, and Inflammation[J] . Ping-Yen Liu,Yen-Wen Liu,Li-Jen Lin,Jyh-Hong Chen,James K. Liao.Circulation . 2009 (1)

[5] Extracellular matrix turnover and inflammatory markers independently predict functional status and outcome in chronic heart failure [J].

Radauceanu, Anca ;

Ducki, Camille ;

Virion, Jean-Marc ;

Rossignol, Patrick ;

Mallat, Ziad ;

McMurray, John ;

Van Veldhuisen, Dirk J. ;

Tavazzi, Luigi ;

Mann, Douglas L. ;

Capiaumont-Vin, Josette ;

Li, Minjiang ;

Hanriot, Didier ;

Zannad, Faiez .

JOURNAL OF CARDIAC FAILURE, 2008, 14 (06) :467-474

[6] Preoperative statins for the prevention of atrial fibrillation after cardiothoracic surgery [J].

Lertsburapa, Kirkeith ;

White, C. Michael ;

Kluger, Jeffrey ;

Faheem, Osman ;

Hammond, Jonathon ;

Coleman, Craig I. .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2008, 135 (02) :405-411

[7]

Atorvastatin Pretreatment Improves Outcomes in Patients With Acute Coronary Syndromes Undergoing Early Percutaneous Coronary Intervention[J] . Giuseppe Patti,Vincenzo Pasceri,Giuseppe Colonna,Marco Miglionico,Dionigi Fischetti,Gennaro Sardella,Antonio Montinaro,Germano Di Sciascio.Journal of the American College of Cardiology . 2007 (12)

[8] Statin therapy is associated with lower mortality among patients with severe heart failure [J].

Mozaffarian, D ;

Nye, R ;

Levy, WC .

AMERICAN JOURNAL OF CARDIOLOGY, 2004, 93 (09) :1124-1129

[9]

ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary[J] . Elliott M. Antman,Daniel T. Anbe,Paul Wayne Armstrong,Eric R. Bates,Lee A. Green,Mary Hand,Judith S. Hochman,Harlan M. Krumholz,Frederick G. Kushner,Gervasio A. Lamas,Charles J. Mullany,Joseph P. Ornato,David L. Pearle,Michael A. Sloan,Sidney C. Smith,Elliott M. Antman,Sidney C. Smith,Joseph S. Alpert,Jeffrey L. Anderson,David P. Faxon,Valentin Fuster,Raymond J. Gibbons,Gabriel Gregor

[10]

Pathophysiology of vascular endothelium and circulating platelets: implications for coronary revascularisation and treatment[J] . Giovanni Amoroso,Dirk J. van Veldhuisen,René A. Tio,Mario Mariani.International Journal of Cardiology . 2001 (2)

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