肺炎支原体与支气管哮喘

被引：38

作者：

陈志敏

机构：

[1] 浙江大学医学院附属儿童医院呼吸科

来源：

临床儿科杂志 | 2011年 / 29卷 / 08期

关键词：

肺炎支原体; 哮喘; 儿童;

D O I：

暂无

中图分类号：

R725.6 [小儿呼吸系及胸部疾病];

学科分类号：

摘要：

肺炎支原体(MP)已成为儿童呼吸道感染的重要病原之一。大量证据表明,MP感染可引起或诱发哮喘的急性发作并导致哮喘慢性症状难以控制。但迄今为止,MP感染诱发或引起哮喘的机制仍不清楚,可能与气道黏膜的损伤、IgE介导的Ⅰ型变态反应及细胞因子和炎症介质的作用有关。文章重点介绍MP感染与哮喘的相关性及其可能的机制。

引用

页码：701 / 704

页数：4

共 6 条

[1] The Change of Asthma-associated Immunological Parameters in Children with Mycoplasma pneumoniae Infection [J].

Tang, Lan Fang ;

Shi, Yi Chen ;

Xu, Ying Chun ;

Wang, Cai Fu ;

Yu, Zhong Sheng ;

Chen, Zhi Min .

JOURNAL OF ASTHMA, 2009, 46 (03) :265-269

[2]

Mycoplasma pneumoniae infection in a pediatric population: Analysis of soluble immune markers as risk factors for asthma[J] . Jaythoon Hassan,Fiona Irwin,Seamus Dooley,Jeff Connell.Human Immunology . 2008 (12)

[3] Internalization and intracellular survival of Mycoplasma pneumoniae by non-phagocytic cells [J].

Yavlovich, A ;

Tarshis, M ;

Rottem, S .

FEMS MICROBIOLOGY LETTERS, 2004, 233 (02) :241-246

[4]

Mycoplasma pneumoniae –induced activation and cytokine production in rodent mast cells[J] . Kristen L. Hoek,Gail H. Cassell,Lynn B. Duffy,T.Prescott Atkinson.The Journal of Allergy and Clinical Immunology . 2002 (3)

[5] A link between chronic asthma and chronic infection [J].

Martin, RJ ;

Kraft, M ;

Chu, HW ;

Berns, EA ;

Cassell, GH .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 107 (04) :595-601

[6]

Increased serum interleukin-5 and vascular endothelial growth factor in children with acute mycoplasma pneumonia and wheeze .2 Choi IS,Byeon JH,Yoo Y,et al. Pediatr Pulmonol . 2009

← 1 →