子宫动脉栓塞术治疗症状性肌壁间子宫肌瘤的疗效及对卵巢功能的影响附视频

被引:43
作者
冯丽霞 [1 ]
张胜华 [2 ]
辛玲丽 [2 ]
曹单 [2 ]
刘冬萍 [1 ]
机构
[1] 解放军第医院妇产科
[2] 第二军医大学上海长征医院妇产科
关键词
子宫肌瘤; 栓塞; 子宫动脉; 卵巢功能;
D O I
暂无
中图分类号
R737.33 [子宫肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
目的探讨子宫动脉栓塞术治疗症状性肌壁间子宫肌瘤的疗效及对卵巢功能的影响。方法 2007年2月~2010年6月对40例症状性肌壁间子宫肌瘤经皮右侧股动脉穿刺,插入导管选择进入子宫动脉,利用聚乙烯醇颗粒行双侧子宫动脉栓塞术。比较术前及术后3、6个月血红蛋白、FSH、LH、E2和肌瘤体积。结果栓塞成功率100%,术后6个月血红蛋白(102.1±9.8)g/L,显著高于术前(75.4±9.7)g/L及术后3个月(80.2±7.6)g/L(q=18.577,P<0.05;q=15.237,P<0.05);术后6个月肌瘤体积(54.7±19.8)cm3,显著小于术前(100.6±20.2)cm3及术后3个月(92.2±16.6)cm3(q=15.331,P<0.05;q=12.525,P<0.05);术后3个月血红蛋白和肌瘤体积与术前相比无统计学差异(q=3.340,P>0.05;q=2.806,P>0.05)。FSH术后3个月(6.09±1.32)IU/ml,显著高于术前(5.15±1.13)IU/ml及术后6个月(5.24±1.07)IU/ml(q=5.046,P<0.05;q=4.563,P<0.05);LH术前(7.12±1.01)IU/ml,术后3、6个月分别为(6.93±0.98)、(7.23±0.99)IU/ml,无统计学差异(F=0.93,P=0.396);E2术后3、6个月分别为(270.40±26.60)、(284.20±28.46)pg/ml,显著低于术前(298.60±39.42)pg/ml(q=5.574,P<0.05;q=2.846,P<0.05)。结论 UAE治疗症状性肌壁间子宫肌瘤能有效改善贫血,缩小肌瘤体积,但对术后卵巢近期功能产生一定影响。
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页码:808 / 810+827 +827
页数:4
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