基于TLR2/MyD88/NF-κB信号通路探讨针灸治疗肠易激综合征的机制

被引：18

作者：

李丹丹 ^{[1
]}

裴丽霞 ^{[2
]}

耿昊 ^{[2
]}

陈璐 ^{[2
]}

吴晓亮 ^{[2
]}

宋亚芳 ^{[1
]}

翁晟捷 ^{[1
]}

孙建华 ^{[2
]}

机构：

[1] 南京中医药大学

[2] 南京中医药大学附属医院

来源：

辽宁中医杂志 | 2018年 / 45卷 / 02期

关键词：

肠易激综合征; 针灸; TLR2/My D88/NF-κB; 机制;

D O I：

10.13192/j.issn.1000-1719.2018.02.048

中图分类号：

R245 [针灸学、针灸疗法];

学科分类号：

100517 [针灸学];

摘要：

肠易激综合征(IBS)的发病率近年来逐年上升,治疗药物种类繁多,但并不能取得满意疗效。针灸治疗IBS在临床应用广泛,疗效确切,但对于针灸治疗IBS机制尚不清楚,从在脑-肠轴、肠道炎症和免疫紊乱等方面论述较多,文章从PI-IBS中存在肠道低度炎症研究出发,以TLR2/My D88/NF-κB信号通路为切入点,阐明针灸治疗IBS的可能作用机制,为临床针灸对IBS的治疗提供依据。

引用

页码：366 / 369

页数：4

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