<正> BACKGROUND: Single method such as Non-stemondal anti-inflammatory drugs(NSAID), intraarticular injection of natrium hyalunate, needle relaxing, physical treatment, functional exercises is often reported to treat degenerative gonarthritis. But multiple lesions of knee in degenerative gonarthritis indicate that single methods have some limit in treatment of degenerative gonarthritis.OBJECTIVE: To observe clinical effects of comprehensive treatment on dengenerative gonarthritis.