急性重症胰腺炎血行感染患者肠屏障功能障碍的临床研究

被引:10
作者
张越新
机构
[1] 浙江省绍兴市人民医院急诊科
关键词
急性重症胰腺炎; 血行感染; 肠屏障功能障碍;
D O I
暂无
中图分类号
R576 [胰腺疾病];
学科分类号
100201 [内科学];
摘要
目的探讨急性重症胰腺炎血行感染患者与肠道屏障的临床相关性研究,并观察急性重症胰腺炎血行感染和术后感染之间的联系。方法对我院40例接受急性重症胰腺炎治疗并确诊为血行感染的患者进行临床分组治疗,对照组采用常规治疗,治疗组在对照组治疗基础上实施肠屏障早期保护措施,比较两组胃肠功能评分和APACHEⅡ评分、C-反应蛋白(CRP)、血清肿瘤坏死因子-α(TNF-α)、血浆内毒素水平(LPS)、尿乳果糖/甘露醇值(L/M),并对两组患者的治疗后一般情况进行比较。结果观察组治疗后APACHEⅡ评分、CRP、TNF-α、LPS均较治疗前有显著下降,与对照组比较差异亦有高度统计学意义(P<0.01)。结论早期进行肠屏障功能保护能有效提高患者胃肠功能,降低肠屏障通透性和炎性反应。
引用
收藏
页码:33 / 35
页数:3
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