理想心血管健康行为和因素对新发缺血性脑卒中的影响

被引:18
作者
王艳秀 [1 ]
吴寿岭 [1 ]
高竞生 [1 ]
郑晓明 [1 ]
安丽杰 [1 ]
田琪 [1 ]
侯国盛 [1 ]
赵海燕 [1 ]
韩艳华 [2 ]
金成 [1 ]
机构
[1] 河北联合大学附属开滦医院心内科
[2] 迁安县人民医院
关键词
理想心血管健康行为和因素; 缺血性脑卒中; 队列研究;
D O I
10.16439/j.cnki.1673-7245.2012.04.037
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
100204 [神经病学];
摘要
目的探讨理想心血管健康行为和因素对新发缺血性脑卒中的影响。方法采用前瞻性队列研究方法,以参加2006-07-2007-10开滦集团健康查体的职工为研究对象,排除既往患脑梗死、心肌梗死及与该研究有关的数据和资料不全者,最终91698名职工进入观察队列,观察随访该队列发生新发缺血性脑卒中的情况;依据美国心脏协会定义的理想心血管健康行为和因素,用K-M法计算不同理想心血管健康行为和因素组的缺血性脑卒中累积发病率,并经Log-rank检验;采用Cox比例风险模型分缺血性脑卒中的影响因素。结果具备5~7项理想心血管健康行为和因素的个体只占研究人群的9.1%,其中具备所有7项的只有93例,占研究人群的0.1%,不足4项者占69.4%。具有0~1、2、3、4、5~7项理想心血管健康行为和因素的人群缺血性脑卒中的累积发病率逐渐降低(P<0.01);Cox比例风险模型表明,校正性别、年龄、收入水平、受教育水平后,具备1~6项理想心血管健康行为和因素的人群发生缺血性脑卒中的风险为无健康行为和因素人群的0.99、0.71、0.51、0.35、0.24、0.28倍。结论理想心血管健康行为和因素对脑血管具有保护作用,随着理想心血管健康行为和因素的个数增多,缺血性脑卒中的累积发病率呈下降趋势。
引用
收藏
页码:342 / 346
页数:5
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