联合应用 LAK 细胞及 IL-2治疗裸鼠脑胶质瘤的研究

被引:2
作者
谭岩
索敬贤
王江滨
机构
[1] 白求恩医科大学一院脑外科
[2] 白求恩医科大学一院内一科
关键词
脑肿瘤; LAK 细胞; 有丝分裂因子,淋巴细胞;
D O I
暂无
中图分类号
学科分类号
摘要
本文报道了通过人脑胶质瘤细胞株 U251建立裸鼠脑胶质瘤模型,应用自制的 IL-2诱导产生 LAK 细胞,输入脑胶质瘤裸鼠体内的治疗结果。结果表明,LAK 细胞在体外对脑胶质瘤细胞具有直接杀伤作用,输入体内后可有效地限制肿瘤的生长速度,延长带瘤动物的生存时间。其中联合应用 LAK 及 IL 2较单纯应用 LAK 组效果更为明显。可见,联合应用 LAK 及 IL-2将可能成为脑胶质瘤的一种治疗方法。
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页码:38 / 40+81
页数:4
相关论文
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