人肾间质细胞培养的研究

被引:13
作者
王伟铭
姚建
曹红娣
楼鼎秀
机构
[1] 上海第二医科大学附属瑞金医院肾脏科
关键词
细胞培养; 成纤维细胞; 小管上皮细胞; 细胞转化; 肾间质纤维化;
D O I
暂无
中图分类号
R692 [肾疾病];
学科分类号
1002 ; 100210 ;
摘要
肾间质细胞,尤其是成纤维细胞,在肾间质纤维化过程中起重要的作用。利用人肾髓质组织,成功地分离培养间质成纤维细胞,根据细胞形态及细胞结构蛋白(细胞角蛋白阴性、波形蛋白阳性和成纤维细胞表面抗原阳性)确定为成纤维细胞,同时根据细胞形态及细胞结构蛋白变化,提出成纤维细胞的增多部分是由小管上皮细胞转化为成纤维细胞。
引用
收藏
页码:455 / 457
页数:3
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