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INRA, Ctr Clermont Ferrand Theix, Unite Malad Metab & Micronutriments, Ctr Rech Nutr Humaine Auvergne, F-63122 St Genes Champanelle, France INRA, Ctr Clermont Ferrand Theix, Unite Malad Metab & Micronutriments, Ctr Rech Nutr Humaine Auvergne, F-63122 St Genes Champanelle, France