再生障碍性贫血骨髓造血微环境的研究进展

被引:2
作者
赵俊梅
房佰俊
机构
[1] 郑州大学附属肿瘤医院血液科
关键词
再生障碍性贫血; 骨髓; 造血微环境;
D O I
暂无
中图分类号
R556.5 [再生障碍性贫血和骨髓硬化性贫血];
学科分类号
摘要
再生障碍性贫血是一种获得性骨髓造血功能衰竭性疾病,其发病机制复杂,早期即有研究证明支持造血功能的骨髓造血微环境异常。骨髓造血微环境是一个由骨髓基质细胞、细胞外基质及多种细胞因子组成的复杂网状结构,各成分相互作用共同支持正常造血。近年来研究发现,许多血液系统疾病的发生与骨髓造血微环境有关,研究骨髓造血微环境对于了解再生障碍性贫血的发病机制及提供有效的治疗方法有重要作用,本研究就有关再生障碍性贫血患者骨髓造血微环境方面的研究进展作一综述。
引用
收藏
页码:77 / 79
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