沿脑-肠轴探讨肠易激综合征的可能机制

被引：11

作者：

林艺娟

王承党

机构：

[1] 福建医科大学附属第一医院消化内科

来源：

医学综述 | 2008年 / 20期

关键词：

肠易激综合征; 内脏高敏感性; 脑-肠轴; 神经-内分泌-免疫;

D O I：

暂无

中图分类号：

R574.4 [肠道功能紊乱];

学科分类号：

1002 ; 100201 ;

摘要：

肠易激综合征(IBS)是在特殊介质的基础上,以神经-内分泌-免疫系统为中介,以社会心理因素刺激为扳机而触发的心身疾病,迄今发病机制尚不明朗,内脏高敏感性作为其主要的最广为接受的病理生理机制备受瞩目,目前认为各种因素导致的外周和(或)中枢致敏是其重要的发病机制。本文综合近年来国内外学者的研究成果,从神经-内分泌-免疫网络失调这一角度探讨IBS患者内脏高敏感性的外周和中枢机制。

引用

页码：3138 / 3141

页数：4

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