针灸、推拿及中药外敷对腰椎间盘突出的临床疗效及血清TXB2、IL-1β、IL-10水平对比

被引：19

作者：

丁灿群 ^{[1
]}

张盛强 ^{[1
]}

张云海 ^{[2
]}

高群兴 ^{[1
]}

谭啟恩 ^{[1
]}

机构：

[1] 广州中医药大学附属佛山中医院骨五科(推拿科)广东佛山

[2] 广州中医药大学附属佛山中医院重症医学科

来源：

现代生物医学进展 | 2021年 / 21卷 / 14期

关键词：

针灸; 推拿; 中药外敷; 腰椎间盘突出; 临床疗效; 炎症反应;

D O I：

10.13241/j.cnki.pmb.2021.14.028

中图分类号：

R274.9 [现代医学骨伤科疾病];

学科分类号：

100210 [外科学];

摘要：

目的:研究针灸、推拿及中药外敷对腰椎间盘突出的临床疗效及血清血栓素(thromboxane,TXA2)、白细胞介素-1β(Interleukin-1β)、白细胞介素-10(Interleukin-10 IL-10)水平对比。方法:选取2019年1月至2020年12月的80例腰椎间盘突出患者。按照随机数表法分为观察组(n=41)和对照组(n=39),对照组采用中药外敷治疗,观察组采用针灸、推拿及中药外敷联合治疗。对比两组治疗效果,治疗前后日本骨科协会评估治疗分数(Japanese Orthopaedic Association Scores JOA)、视觉模拟评分法(visual analogue scale VAS)评分情况变化,血清TXB2、IL-1β、IL-10水平变化,腰椎功能及腰部关节活动度,不良反应发生率。结果:治疗后,观察组总有效率显著高于对照组[95.12%(39/41)vs71.79%(28/39)](P<0.05);JOA显著高于对照组[(23.19±3.21)分vs(17.62±2.65)分](P<0.05),VAS评分显著低于对照组[(2.07±0.38)分vs(3.58±0.61)分](P<0.05);血清TXB2、IL-1β水平均显著低于对照组[(24.37±3.26)μg/L vs(34.08±4.72)μg/L,(0.12±0.03)ng/L vs(0.27±0.05)ng/L](P<0.05);血清IL-10水平显著低于对照组[(85.82±7.03)pg/mL vs(57.28±6.31)pg/mL](P<0.05);功能障碍指数(Oswestry disability index)显著低于对照组[(37.81±6.23)%vs(68.02±8.91)%](P<0.05);腰部关节活动度显著高于对照组[(80.36±0.82)°vs(71.27±0.6)°](P<0.05);两组不良反应对比无显著差异(P>0.05)。结论:针灸、推拿及中药外敷对腰椎间盘突出的临床疗效显著,可有效改善患者的临床症状,缓解疼痛,抑制炎症因子TXB2、IL-1β表达,促进抗炎因子IL-10水平升高,安全有效。

引用

页码：2730 / 2734

页数：5

共 18 条

[1]

EVALUATION OF THE EFFECTIVENESS OF TRANSFORAMINAL EPIDURAL STEROID INJECTION IN FAR LATERAL LUMBAR DISC HERNIATIONS [J].

Evran, Sevket ;

Katar, Salim .

IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE, 2021, 74 (1-2) :27-32

[2]

Does oblique lumbar interbody fusion promote adjacent degeneration in degenerative disc disease: A finite element analysis [J].

Du, Cheng-Fei ;

Cai, Xin-Yi ;

Gui, Wu ;

Sun, Meng-Si ;

Liu, Zi-Xuan ;

Liu, Chun-Jie ;

Zhang, Chun-Qiu ;

Huang, Yun-Peng .

COMPUTERS IN BIOLOGY AND MEDICINE, 2021, 128

[3]

Effect of Panchatikta Ksheera basti with Kati basti in Katishoola w. s. r lumbar disc degeneration – A clinical study.[J].Kaalia Neelam;Bhatted Santosh;Acharya S.Indian Journal of Health Sciences and Biomedical Research (KLEU).2021, 1

[4]

Non-surgical treatment with XSHHD for ruptured lumbar disc herniation: a 3-year prospective observational study [J].

Dai, Feng ;

Dai, Yu Xiang ;

Jiang, Hong ;

Yu, Peng Fei ;

Liu, Jin Tao .

BMC MUSCULOSKELETAL DISORDERS, 2020, 21 (01)

[5]

Investigation of Alterations in the Lumbar Disc Biomechanics at the Adjacent Segments After Spinal Fusion Using a Combined In Vivo and In Silico Approach..[J].Zhou Chaochao;Cha Thomas;Wang Wei;Guo Runsheng;Li Guoan.Annals of biomedical engineering.2020,

[6]

Intradiscal Delivery of Anabolic Growth Factors and a Metalloproteinase Inhibitor in a Rabbit Acute Lumbar Disc Injury Model [J].

Gandhi, Sapan D. ;

Maerz, Tristan ;

Mitchell, Sean ;

Bachison, Casey ;

Park, Daniel K. ;

Fischgrund, Jeffrey S. ;

Baker, Kevin C. .

INTERNATIONAL JOURNAL OF SPINE SURGERY, 2020, 14 (04) :585-593

[7]

Association between serum levels of interleukin-6 on pain and disability in lumbar disc herniation surgery.[J].Kaveh Haddadi;Saeed Abediankenari;Abbas Alipour;Hamid Ghazvini;Hamed Jafarpour;Leila Asadian;Seid Ketabchi.Asian Journal of Neurosurgery.2020, 3

[8]

A comparative study between laminectomy and laminotomy in patient of lumbar disc prolapse.[J].Pinakin I Vasa;Kamal Sanjay.Indian Journal of Orthopaedics Surgery.2020, 1

[9]

Factors Influencing Early Disc Height Loss Following Lateral Lumbar Interbody Fusion [J].

Kaliya-Perumal, Arun-Kumar ;

Soh, Tamara Lee Ting ;

Tan, Mark ;

Oh, Jacob Yoong-Leong .

ASIAN SPINE JOURNAL, 2020, 14 (05) :601-607

[10]

International Society for the Advancement of Spine Surgery Policy 2019-Surgical Treatment of Lumbar Disc Herniation with Radiculopathy [J].

Lorio, Morgan ;

Kim, Choll ;

Araghi, Ali ;

Inzana, Jason ;

Yue, James J. .

INTERNATIONAL JOURNAL OF SPINE SURGERY, 2020, 14 (01) :1-17

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